Welcome to Rx-Topamax where you can learn all about the popular drug and
its many and uses. Topamax is primarily an anticonvulsant for use in epilepsy
treatment, but recently has been found usefull in weight loss, and mood stabilizaton.
Rx Topamax
Topamax For Epilepsy
Topamax is an anticonvulsant that is chemically unrelated to any other anticonvulsant
or mood regulating medication. Potentially, is could have five mechanisms of
action. They include the blockage of sodium channels (similar to many of the
traditional epileptics), enhancement of GABA-a receptors (an inhibitory neurotransmitter),
inhibitory effect on glutamate receptors, inhibition of L-type high-voltage
calcium ion channels, and a diamox type effect.
Topiramate (brand name Topamax) is only FDA approved for the treatment of people
with seizures. There are few systematic studies that establish the safety or
efficacy of topiramate as a treatment for people with of phenytoin (Dilantin).
Phenytoin lowers the concentration of topiramate in the blood by about 50%.
While topiramate has little effect on the plasma level of carbamazepine, the
latter may decrease the plasma level of topiramate by about 50%. Valproate lowers
the plasma level of topiramate by about 15%. Topomax may lead to decreased effectiveness
of some oral anticontraceptives Mood
stabilizing and weight loss effects The official Topamax web site - The
official Topamax web site FDA white papers - FDA
white papers
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